I tend to see trans humanism as the usual clueless wishful thinking, with little understanding of life and none of the costs and consequences.

Consider the idea of life extension; Given most people live in their cocoons, with little real, deep relations with the world around them and other people, they are all they have, so the instinct to hang on as long as possible is a logical consequence. Yet when people are deeply part of their world, life is more like a sentence in a larger story, where the end is just punctuation and what matters is how well you tie the rest of the story together.

Now if life extension became a thing, in this world, obviously it would be monetized and the larger costs hidden. Much like with our current society, where we can just stay in our rooms and safe spaces and everything is brought to us, as the rest of the planet is pillaged to make it possible. How much do you suppose it would increase organ harvesting, not to mention one more enormous scam by the medical industry?

As for somehow becoming smarter and more aware, obviously it would only be about what is pleasurable and convenient, not all those actual messy details of life we do our best to ignore.

The fact is that what defines us, also limits us and what limits us, also defines us. So if we push the boundaries of our being out a little further, that would simply create a new set of boundaries and the issues arising from them. Much like growing up creates a new set of issues, as the old ones are overcome.

Space travel? How much rocket fuel does it take to just get a moderate sized payload into low earth orbit, not to mention the complexity and cost of doing it right on a regular basis. Then space itself; Do you appreciate just how far it is the closest stars, then having to find one that might be even close to inhabitable? Maybe the Moon and Mars, but the costs are overwhelming, especially for nations already wasting most of their resources in cultural ego gratification schemes.

I still think we need a better grasp of the is, before realistically proposing any oughts, but when are people realistic, except in the aftermath of the occasional reality check.