I think the more important issues go to the underlaying logic and how it has evolved, both scientifically and religiously.
Both assume order as the goal, rather than a useful tool for expanding knowledge.
The order we extract are signals from the noise. Maps from the territory. They necessarily exist as edits of the larger picture, necessitating built in flaws to make them work.
If we tried including all information from the territory in the map, it would revert back to noise.
For example, epicycles were brilliant math, but lousy physics, because they were built around our point of view. Which still infects, not only knowledge, but our process of building a knowledge base, where one generation builds on what it is given and passes it on to the next. Often patching those gaps with whatever works, than really reviewing the underlaying principles. Adding more cycles.
So if the basic philosophy is, "shut up and calculate," it doesn't take into account that, "garbage in, garbage out." Computers and mathematicians are not good at looking outside the box/program/model/order.
It becomes about where the program leads, not whether it really does fit the evidence. Order becomes the goal.
Currently we have a cosmology that keeps adding enormous patches to cover where observations did not correlate with predictions.
Before Inflation, Dark Matter and Dark Energy, the original patch was when it was realized that cosmic redshift increases proportional to distance in all directions, it either meant this redshift was some sort of optical effect, or we are at the center of the universe.
Given the light was not otherwise distorted, aka, "tired," the idea became that space itself must be expanding, because "spacetime!"
Which ignores the fact that the central premise of General Relativity and spacetime is the speed of light is always measured as a Constant. If space were to relativistically expand, the speed of light would have to increase, in order to remain constant, but that wouldn't explain the redshift, which is supposedly due to the light taking longer to cross this expanding space.
Two metrics are being derived from the same light. One based on speed and the other based on spectrum. If the speed were the numerator, it would be a "tired light" theory, but as an "expanding space" theory, the speed of light is still the explicit denominator. The metric against which this expansion is measured and effected. Under all the academic authority, it's bad grade school math.
That's what happens when the social effects end up dictating the allowed order. More about working within the program, than any larger purpose.
Eventually a reality check comes along.
Looking at all the various cultural, religious, economic, political and yes, even scientific models reaching the point of reductio ad absurdum, we are in for The Mother of all Reality Checks.