To culture, good and bad are some cosmic conflict between righteousness and evil, while in nature, it's the basic biological binary of beneficial and detrimental. That's because it is the function of culture to get the social organism acting as one. So when there is dissonance, it's like the immune system kicks in.
Unfortunately there are also autoimmune disorders, where this sense of the foreign attacks the functions of the organism.
Part of the problem is we are linear, goal oriented creatures, in a cyclical, circular, feedback generated reality, so we tend to treat life as a race, when it's more of a dance.
I have to say, in 2020, I just wrote in Assange/Manning. The levels of corruption and cynicism on all sides are beyond saving.